Genetics and CRISPR: From DNA to Gene Editing
by admin · Genetics and CRISPR
A 15-hour working-knowledge course covering molecular genetics, gene regulation, inheritance, genome-wide association, CRISPR mechanisms, editor design, delivery, approved therapy, applications, and ethics.
Free account, then it's yours: your own private copy with a clean slate and its own review schedule.
Sign up free to take it →4
modules
13
lessons
14.7h
estimated work · target 15h
What's inside
52 tasks · 30 flashcards · 62 concepts · 27 recall prompts
Sample recall prompts — this is what studying it feels like
- Explain DNA directionality and why antiparallel strands matter for copying.
- Compare DNA and RNA in structure and role.
- Why does replication produce leading and lagging strands?
Syllabus
Molecular Genetics: DNA to Protein
Builds the molecular foundation for genetics and editing: nucleic acids, replication, repair, transcription, RNA processing, translation, and protein effects.
- DNA, RNA, and Genome Architecture reading · flashcard · quiz · note · 5 cards
- Replication, Repair, and Mutation teach_back · reading · flashcard · quiz · 5 cards
- Transcription and RNA Processing reading · note · quiz · teach_back
- Translation and Protein Function reading · note · quiz · teach_back
Regulation, Inheritance, and Variation
Connects molecular mechanisms to gene regulation, chromatin, Mendelian inheritance, linkage, population variation, and GWAS.
- Gene Regulation, Chromatin, and Epigenetics reading · flashcard · quiz · note · 5 cards
- Mendelian Inheritance, Meiosis, and Linkage teach_back · reading · note · quiz
- Population Genetics, Polygenic Traits, and GWAS reading · note · quiz · essay
CRISPR Tools and Delivery
Explains Cas9 targeting, guide design, off-target risk, base editing, prime editing, editor variants, and delivery choices.
- CRISPR-Cas9 Mechanism note · reading · flashcard · quiz · 5 cards
- Guide Design, Base Editors, and Prime Editors reading · note · quiz · teach_back
- Delivery: Viral Vectors, LNPs, Ex Vivo, and In Vivo Editing essay · reading · flashcard · quiz · 5 cards
Applications, Case Studies, and Ethics
Applies the framework to Casgevy, in vivo editing, agricultural editing, germline ethics, enhancement, governance, and capstone review.
- Case Study: Casgevy for Sickle Cell Disease reading · flashcard · quiz · teach_back · 5 cards
- Current Applications: In Vivo Editing and Agriculture note · reading · note · quiz
- Ethics, Governance, and Capstone Proposal Review reading · note · quiz · project